Description

1,4,7,10,13,16-Hexaazacyclooctadecane is a versatile macrocyclic polyamine ligand, also known as hexacyclen, with the CAS number 296-35-5. This compound is valued for its strong and selective chelating properties towards various metal cations, making it a critical building block in coordination chemistry and supramolecular science. It is essential for researchers and manufacturers in the fields of chemical synthesis, catalysis, and the development of advanced materials and diagnostic agents.

Application

• Coordination Chemistry & Catalyst Synthesis: Serves as a fundamental ligand for constructing transition metal complexes used in homogeneous catalysis and as enzyme mimics.
• Supramolecular Chemistry: Acts as a key component in the design of molecular hosts, sensors, and switches due to its pre-organized nitrogen donor sites.
• Analytical Chemistry & Chelation Therapy: Used in the development of selective chelating agents for metal ion separation, detection, and potential therapeutic applications.
• Material Science: Employed in the synthesis of metal-organic frameworks (MOFs) and functional polymers with tailored properties.
• Bioconjugation & Labeling: Facilitates the attachment of metal-based probes or contrast agents to biomolecules for imaging and diagnostic purposes.
• Academic & Industrial Research: A fundamental reagent for exploratory research in inorganic chemistry, bioinorganic chemistry, and nanotechnology.

Basic Information

Product Name	1,4,7,10,13,16-Hexaazacyclooctadecane
CAS No.	296-35-5
Molecular Formula	C12H30N6
Molecular Weight	258.41 g/mol
Synonyms	Hexacyclen; 1,4,7,10,13,16-Hexaazacyclooctadecane; 1,4,7,10,13,16-Hexaazacyclooctadecane (Hexacyclen); 18-Aza-6,9,12,15-tetraoxa-1,4,7,10,13,16-hexaazacyclooctadecane; 1,4,7,10,13,16-Hexaaza-18-crown-6; 18-Aza-6,9,12,15-tetraoxa-1,4,7,10,13,16-hexaazacyclooctadecane; 1,4,7,10,13,16-Hexaazacyclooctadecane, Hexacyclen
EINECS	206-055-9

Quality Control

Our 1,4,7,10,13,16-Hexaazacyclooctadecane is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with specified standards. We support custom synthesis and can tailor purity grades to meet specific research or industrial requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.