Description

1,4,8,11-Tetraoxacyclotetradecane is a versatile macrocyclic polyether, commonly known as a crown ether, with the CAS number 295-40-9. Its unique structure enables it to selectively bind cations, making it a critical tool for phase-transfer catalysis and ion transport studies in advanced chemical synthesis. This compound is essential for researchers and manufacturers in the pharmaceutical, materials science, and specialty chemical industries who require precise molecular recognition and separation capabilities.

Application

• Phase-Transfer Catalyst (PTC): Facilitates reactions between reagents in immiscible phases, enhancing reaction rates and yields in organic synthesis.
• Ionophore for Sensor Development: Serves as a key component in the fabrication of ion-selective electrodes and chemical sensors for analytical chemistry.
• Molecular Recognition Studies: Used in supramolecular chemistry research to study host-guest interactions and complexation thermodynamics.
• Metal Ion Separation & Extraction: Employed in processes for the selective extraction and purification of specific metal ions from complex mixtures.
• Polymer & Materials Modification: Acts as an additive to modify the properties of polymers or to create novel functional materials.
• Pharmaceutical Intermediate Synthesis: Utilized in the synthesis of complex drug molecules where selective cation binding is required for specific reaction steps.

Basic Information

Product Name	1,4,8,11-Tetraoxacyclotetradecane
CAS No.	295-40-9
Molecular Formula	C10H20O4
Molecular Weight	204.26 g/mol
Synonyms	14-Crown-4; 1,4,8,11-Tetraoxacyclotetradecane; 14-Crown-4 ether; 1,4,8,11-Tetraoxacyclotetradec-2-ene (common misnomer); Tetraglyme (cyclic); Cyclic tetramer of ethylene oxide; Tetraethylene glycol cyclic ether
EINECS	206-001-3

Quality Control

Our 1,4,8,11-Tetraoxacyclotetradecane is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including assay by GC or HPLC, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and specific impurity profiles are provided with every shipment to guarantee compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product performance.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.