Description

1,7-Diaza-12-Crown-4 is a specialized macrocyclic polyether, or crown ether, distinguished by its nitrogen-containing heteroatoms. This compound is a highly effective and selective complexing agent, particularly for small cations like lithium and sodium, due to its specific cavity size. It is essential for researchers and manufacturers in advanced organic synthesis, catalysis, and materials science who require precise molecular recognition and phase-transfer capabilities. Its unique structure makes it a valuable tool for modifying reaction pathways and isolating specific metal ions.

Application

• Phase-Transfer Catalyst: Facilitates reactions between reagents in immiscible phases, enhancing reaction rates and yields in organic synthesis.
• Metal Ion Complexation & Separation: Selectively binds to alkali and alkaline earth metal ions (e.g., Li⁺, Na⁺) for extraction, sensing, or purification processes.
• Chemical Sensor Development: Serves as a key ionophore in the fabrication of ion-selective electrodes (ISEs) and optical sensors.
• Polymer & Materials Modification: Incorporated into polymers or surfaces to impart ion-binding properties for advanced material applications.
• Academic & Industrial Research: A fundamental reagent for studying host-guest chemistry, supramolecular assembly, and catalysis.
• Pharmaceutical Intermediate Synthesis: Used in the synthesis of complex molecules where controlled metal ion coordination is critical.

Basic Information

Product Name	1,7-Diaza-12-Crown-4
CAS No.	294-92-8
Molecular Formula	C₈H₂₀N₂O₂
Molecular Weight	176.26 g/mol
Synonyms	1,7-Diaza-12-crown-4 ether; 1,7-Diazacyclododecane-4,10-dione; 4,10-Diaza-1,7-dioxacyclododecane; 1,4,7,10-Tetraoxa-13,16-diazacyclooctadecane (systematic alternative); Aza-crown ether; Diaza-crown ether; N,N'-Diaza-12-crown-4; 1,7-Diaza-4,10-dioxacyclododecane
EINECS	206-004-9

Quality Control

Our 1,7-Diaza-12-Crown-4 is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets exacting standards for research and industrial use. A detailed Certificate of Analysis (COA) documenting identity, purity, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.