Description

2-Bromo-2-Methyl-3-(Trimethylsilyl)-Cyclopropanemethanol is a highly functionalized cyclopropane derivative, serving as a versatile and valuable synthetic intermediate in advanced organic chemistry. Its unique structure, featuring bromine, a trimethylsilyl group, and a hydroxymethyl moiety on a strained three-membered ring, makes it a critical building block for constructing complex molecular architectures. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those requiring cyclopropane ring systems for bioactivity or as conformational constraints.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where the cyclopropane moiety can impart unique biological properties.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced materials with tailored properties.
• Organic Synthesis Building Block: Utilized in academic and industrial R&D for cyclopropanation reactions, ring-opening transformations, and the introduction of silicon-containing functional groups.
• Ligand and Catalyst Development: Potential precursor for creating novel chiral ligands or organometallic catalysts used in asymmetric synthesis.

Basic Information

Product Name	2-Bromo-2-Methyl-3-(Trimethylsilyl)-Cyclopropanemethanol
CAS No.	1993417-50-7
Molecular Formula	C9H19BrOSi
Molecular Weight	251.24 g/mol
Synonyms	2-Bromo-2-methyl-3-(trimethylsilyl)cyclopropanemethanol; (2-Bromo-2-methyl-3-(trimethylsilyl)cyclopropyl)methanol; Cyclopropanemethanol, 2-bromo-2-methyl-3-(trimethylsilyl)-; 2-Methyl-2-bromo-3-(trimethylsilyl)cyclopropanemethanol; TMS-Cyclopropane Bromo Alcohol; Bromo-TMS-Cyclopropane Methanol
EINECS	Contact for details

Quality Control

Our 2-Bromo-2-Methyl-3-(Trimethylsilyl)-Cyclopropanemethanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee it meets the stringent requirements of research and process development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to prevent degradation upon opening.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.