Description

n-[3,5-Bis(Trifluoromethyl)Phenyl-N'-[(1R,2R)-2-(11Bs)3,5-Dihydro-4H-Dinaphth[2,1-C:1',2'-E]Azepin-4-Yl]Cyclohexyl]-Thiourea is a sophisticated chiral thiourea derivative designed for advanced chemical synthesis and research. This compound is valued for its role as a highly selective organocatalyst and as a key building block in the development of novel pharmaceuticals and functional materials. It is primarily sought by research institutions and industrial R&D departments focused on asymmetric synthesis, medicinal chemistry, and materials science.

Application

• Asymmetric Organocatalysis: Acts as a chiral hydrogen-bond donor catalyst for enantioselective reactions, including Michael additions and aldol condensations.
• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of complex, biologically active molecules for drug discovery programs.
• Ligand Synthesis: Used to prepare novel chiral ligands for transition metal catalysis, enhancing selectivity in industrial chemical processes.
• Materials Science Research: Employed in the development of advanced organic materials with specific optical or electronic properties.
• Chemical Biology Probes: Utilized in the design of molecular probes to study enzyme mechanisms and protein-ligand interactions.
• Academic & Industrial R&D: A fundamental tool for methodological development in synthetic organic chemistry laboratories worldwide.

Basic Information

Product Name	n-[3,5-Bis(Trifluoromethyl)Phenyl-N'-[(1R,2R)-2-(11Bs)3,5-Dihydro-4H-Dinaphth[2,1-C:1',2'-E]Azepin-4-Yl]Cyclohexyl]-Thiourea
CAS No.	1984862-45-4
Molecular Formula	C36H27F6N3S
Molecular Weight	639.68 g/mol
Synonyms	(1R,2R)-N-[3,5-Bis(trifluoromethyl)phenyl]-N'-[2-(11bS)-4,5-dihydro-3H-dinaphtho[2,1-c:1',2'-e]azepin-4-yl]cyclohexyl]thiourea; (R,R)-3,5-Bis(trifluoromethyl)phenyl Thiourea Dinaphthazepine Cyclohexyl Derivative; Chiral BINOL-Derived Thiourea Organocatalyst; BTFMP-Thiourea Catalyst; Axially Chiral Thiourea; Dinaphthoazepine Thiourea; N-[3,5-Bis(trifluoromethyl)phenyl]-N'-[(1R,2R)-2-((11bS)-3,5-dihydro-4H-dinaphth[2,1-c:1',2'-e]azepin-4-yl)cyclohexyl]thiourea
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and chiral analysis to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) detailing all specifications are available upon request, providing full traceability and assurance for your critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; ensure the container is kept sealed in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.