Description

1,3-Dioxane, 5-Butyl-2-(3',5'-Difluoro[1,1'-Biphenyl]-4-Yl)-, trans- is a high-purity, advanced pharmaceutical intermediate characterized by its specific stereochemistry and functionalized biphenyl-dioxane structure. This compound matters for its role as a critical building block in the synthesis of complex organic molecules, particularly in medicinal chemistry. It is primarily needed by R&D laboratories and production facilities in the pharmaceutical and agrochemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the difluorobiphenyl moiety contributes to biological activity and environmental stability.
• Liquid Crystal Materials: Acts as a precursor in the synthesis of fluorinated liquid crystals for display technologies, leveraging its rigid, fluorinated biphenyl core.
• Organic Light-Emitting Diodes (OLEDs): Employed in the development of electron-transport or host materials for OLED devices due to its favorable electronic properties and molecular architecture.
• Chemical Research: Utilized in academic and industrial R&D for studying stereoselective reactions and as a model compound in methodology development.
• Complex Ligand Synthesis: Functions as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	1,3-Dioxane, 5-Butyl-2-(3',5'-Difluoro[1,1'-Biphenyl]-4-Yl)-, trans-
CAS No.	1983993-59-4
Molecular Formula	C₂₀H₂₂F₂O₂
Molecular Weight	332.39 g/mol
Synonyms	trans-5-Butyl-2-(3',5'-difluoro-[1,1'-biphenyl]-4-yl)-1,3-dioxane; (trans)-5-Butyl-2-(3',5'-difluorobiphenyl-4-yl)-1,3-dioxane; 5-Butyl-2-(3,5-difluoro[1,1'-biphenyl]-4-yl)-1,3-dioxane, trans-; Biphenyl-dioxane derivative CAS 1983993-59-4; 4'-(5-Butyl-1,3-dioxan-2-yl)-3,5-difluorobiphenyl; 2-(3',5'-Difluorobiphenyl-4-yl)-5-butyl-1,3-dioxane; Difluorobiphenyl dioxane intermediate
EINECS	Contact for details

Quality Control

Our 1,3-Dioxane, 5-Butyl-2-(3',5'-Difluoro[1,1'-Biphenyl]-4-Yl)-, trans- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for stereochemical purity and NMR for structural confirmation, to ensure compliance with exacting R&D and production standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and should be handled under an inert atmosphere if prolonged exposure is anticipated to prevent potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0% (Area %)
Chiral Purity (Chiral HPLC)	≥ 99.0% (trans-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.