Description

(3R,4R)-3-Amino-4-Hydroxy-Tetrahydropyran Hcl CAS NO 1980007-33-7 is a high-purity chiral building block and pharmaceutical intermediate of significant synthetic utility. This compound is valued for its defined stereochemistry, which is crucial for imparting specific biological activity in final active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and manufacturers in the pharmaceutical and fine chemical industries engaged in the development and production of novel therapeutics.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug molecules, particularly those targeting infectious diseases or metabolic disorders.
• Organic Synthesis Building Block: Used in asymmetric synthesis to construct more complex molecular architectures with high enantiomeric purity.
• Research & Development (R&D): Employed in medicinal chemistry for lead optimization and the discovery of new chemical entities.
• Process Chemistry: Serves as a starting material or intermediate in the scale-up and commercial manufacturing of APIs under GMP conditions.
• Catalyst and Ligand Preparation: Potential precursor for the development of chiral catalysts or ligands used in enantioselective transformations.

Basic Information

Product Name	(3R,4R)-3-Amino-4-Hydroxy-Tetrahydropyran Hydrochloride
CAS No.	1980007-33-7
Molecular Formula	C5H12ClNO2
Molecular Weight	153.61 g/mol
Synonyms	(3R,4R)-3-Amino-4-hydroxytetrahydro-2H-pyran hydrochloride; (3R,4R)-3-Amino-4-hydroxytetrahydropyran HCl; 3-Amino-4-hydroxy-tetrahydropyran, (3R,4R)-, hydrochloride; Tetrahydro-2H-pyran-3-amine, 4-hydroxy-, (3R,4R)-, hydrochloride; 1980007-33-7; (3R,4R)-AHTP-HCl
EINECS	Contact for details

Quality Control

Our (3R,4R)-3-Amino-4-Hydroxy-Tetrahydropyran HCl is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and manufacturing. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.