Description

3-Boc-5,5-Dimethyl-1,2,3-Oxathiazolidine 2,2-Dioxide is a high-purity, specialized heterocyclic building block used in advanced organic synthesis. This compound is valued for its role as a protected sulfamidate reagent, enabling the controlled introduction of nitrogen and sulfur functionalities. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of sulfonamide and sulfamate-containing drug candidates, including protease inhibitors and enzyme modulators.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides that require specific sulfamoyl or sulfonyl motifs.
• Chemical Biology Probes: Serves as a precursor for creating activity-based probes and labeling reagents to study enzyme function and protein interactions.
• Polymer Science: Employed in the research of specialty polymers and functional materials where the sulfamidate group can impart unique properties.
• Academic & Contract Research: Essential for methodological development in organic chemistry, particularly in studies involving ring-opening reactions and heteroatom transfer.
• Peptide Mimetics: Facilitates the incorporation of non-peptide, sulfamate-based isosteres into peptide backbones to enhance metabolic stability.

Basic Information

Product Name	3-Boc-5,5-Dimethyl-1,2,3-Oxathiazolidine 2,2-Dioxide
CAS No.	1956378-90-7
Molecular Formula	C9H17NO5S
Molecular Weight	251.30 g/mol
Synonyms	1,2,3-Oxathiazolidine, 5,5-dimethyl-3-[(1,1-dimethylethoxy)carbonyl]-, 2,2-dioxide; tert-Butyl 5,5-dimethyl-1,2,3-oxathiazolidine-3-carboxylate 2,2-dioxide; N-Boc-5,5-dimethyl-1,2,3-oxathiazolidine 2,2-dioxide; 3-(tert-Butoxycarbonyl)-5,5-dimethyl-1,2,3-oxathiazolidine 2,2-dioxide; Boc-protected dimethylsulfamidate; Boc-Dimethylsulfamoyl Cyclic Sulfate
EINECS	Contact for details

Quality Control

Every batch of 3-Boc-5,5-Dimethyl-1,2,3-Oxathiazolidine 2,2-Dioxide is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.