Description

Carbamic Acid, n-[(3S,4R)-3-Aminotetrahydro-2H-Pyran-4-Yl]-, 1,1-Dimethylethyl Ester is a high-purity, chiral building block of significant interest in advanced organic synthesis. This compound matters because it serves as a critical intermediate for constructing complex molecules with precise stereochemistry, a fundamental requirement in modern pharmaceutical development. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly those targeting neurological and metabolic pathways.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, especially for central nervous system (CNS) and antiviral therapies.
• Agrochemical Synthesis: Used in the production of advanced, enantiomerically pure pesticides and herbicides for enhanced efficacy and environmental safety.
• Peptidomimetic Research: Serves as a constrained scaffold in the design of peptide analogs and protease inhibitors.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds and molecular probes for studying biological mechanisms.
• Catalyst Ligand Precursor: Can be utilized to develop novel chiral ligands for asymmetric catalysis.
• Academic & Contract Research: Essential for synthetic chemistry research in universities and contract research organizations (CROs).

Basic Information

Item	Details
Product Name	Carbamic Acid, n-[(3S,4R)-3-Aminotetrahydro-2H-Pyran-4-Yl]-, 1,1-Dimethylethyl Ester
CAS No.	1951459-69-0
Molecular Formula	C10H20N2O3
Molecular Weight	216.28 g/mol
Synonyms	tert-Butyl N-[(3S,4R)-3-Aminooxan-4-yl]carbamate; (3S,4R)-4-[(tert-Butoxycarbonyl)amino]oxan-3-amine; Boc-4-amino-3-aminotetrahydropyran; (3S,4R)-3-Amino-4-(Boc-amino)tetrahydropyran; 1,1-Dimethylethyl N-[(3S,4R)-3-aminooxan-4-yl]carbamate; (3S,4R)-4-(Boc-amino)-3-aminotetrahydropyran; (3S,4R)-BocNH-THP-3-NH2; 1951459-69-0
EINECS	Contact for details

Quality Control

Our Carbamic Acid, n-[(3S,4R)-3-Aminotetrahydro-2H-Pyran-4-Yl]-, 1,1-Dimethylethyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can compromise product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.