Description

trans-3-(2-Hydroxypropan-2-Yl)Cyclobutane-1-Carboxylic Acid is a high-purity, functionalized cyclobutane derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and valuable chiral building block for the construction of complex molecular architectures. It is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, leveraging its rigid cyclobutane core for unique biological activity.
• Ligand and Catalyst Development: Serves as a precursor for sophisticated ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials with tailored properties.
• Chemical Biology Probes: Useful for constructing molecular probes to study enzyme function and biological pathways due to its functional group handle.
• Custom Synthesis and Contract Manufacturing: A critical starting material for CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	trans-3-(2-Hydroxypropan-2-Yl)Cyclobutane-1-Carboxylic Acid
CAS No.	1940136-70-8
Molecular Formula	C8H14O3
Molecular Weight	158.20 g/mol
Synonyms	trans-3-(2-Hydroxy-2-propyl)cyclobutanecarboxylic acid; 3-(1-Hydroxy-1-methylethyl)cyclobutanecarboxylic acid (trans-); 2-[3-(Carboxy)cyclobutyl]propan-2-ol; Cyclobutanecarboxylic acid, 3-(2-hydroxy-1-methylethyl)-, trans-; (1r,3s)-3-(2-Hydroxypropan-2-yl)cyclobutane-1-carboxylic acid; BCPC Intermediate; CAS 1940136-70-8
EINECS	Contact for details

Quality Control

Our trans-3-(2-Hydroxypropan-2-Yl)Cyclobutane-1-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.