Description

2-Oxabicyclo[2.1.1]Hexane, 1-(Iodomethyl)- is a specialized bicyclic ether derivative featuring a reactive iodomethyl functional group, making it a valuable high-purity building block for advanced organic synthesis. This compound is critical for researchers and process chemists developing novel pharmaceuticals and agrochemicals, where its unique strained-ring structure enables the construction of complex molecular architectures. It is primarily utilized in medicinal chemistry, process R&D, and the synthesis of fine chemicals requiring precise stereochemical control.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for constructing bridged or constrained ring systems.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides that benefit from its unique bicyclic scaffold.
• Ligand and Catalyst Development: Acts as a precursor for synthesizing specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of novel polymers and functional materials with specific thermal or mechanical properties.
• Cross-Coupling Reactions: The iodomethyl group makes it a suitable substrate for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille).
• Radical Chemistry: Utilized as a precursor in radical cyclization and addition reactions to form complex polycyclic structures.

Basic Information

Product Name	2-Oxabicyclo[2.1.1]Hexane, 1-(Iodomethyl)-
CAS No.	1935986-52-9
Molecular Formula	C6H9IO
Molecular Weight	224.04 g/mol
Synonyms	1-(Iodomethyl)-2-oxabicyclo[2.1.1]hexane; 2-Oxabicyclo[2.1.1]hexane, 1-(iodomethyl)-; 1-Iodomethyl-2-oxabicyclo[2.1.1]hexane; (Iodomethyl)oxabicyclo[2.1.1]hexane; Bicyclic iodomethyl ether; Oxabicyclohexane iodomethyl derivative
EINECS	Contact for details

Quality Control

Our 2-Oxabicyclo[2.1.1]Hexane, 1-(Iodomethyl)- is manufactured under controlled conditions to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes rigorous analytical testing including HPLC, GC, and NMR to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Keep away from heat, sparks, and open flame. Due to its light-sensitive and easily oxidized nature, minimize exposure to air and light during handling.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.