Description

(4-Cyanotetrahydro-2H-Pyran-4-Yl)Methyl 4-Methylbenzenesulfonate is a high-value, specialized organic intermediate featuring a unique molecular scaffold that combines a cyanopyran moiety with a tosylate leaving group. This compound matters for its critical role in advanced synthetic chemistry, enabling the construction of complex molecules through nucleophilic substitution and further functionalization of the nitrile group. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those requiring functionalized tetrahydropyran or piperidine ring systems.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where its structural features can impart specific biological activity.
• Ligand and Catalyst Synthesis: Employed for the preparation of specialized ligands and organocatalysts used in asymmetric synthesis and metal complexation.
• Material Science Precursor: Acts as a monomer or cross-linking agent in the development of advanced polymers with specific thermal or chemical resistance properties.
• Chemical Biology Probe Development: Utilized to create molecular probes and tags for studying biological processes, leveraging the reactivity of the tosylate and nitrile groups.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring precise introduction of the (4-cyanotetrahydro-2H-pyran-4-yl)methyl fragment.

Basic Information

Product Name	(4-Cyanotetrahydro-2H-Pyran-4-Yl)Methyl 4-Methylbenzenesulfonate
CAS No.	1934583-18-2
Molecular Formula	C14H17NO4S
Molecular Weight	295.35 g/mol
Synonyms	4-((Tosyloxy)methyl)tetrahydro-2H-pyran-4-carbonitrile; (4-Cyanooxan-4-yl)methyl 4-methylbenzenesulfonate; 4-(Hydroxymethyl)tetrahydro-2H-pyran-4-carbonitrile Tosylate; Tosylate Ester of 4-(Hydroxymethyl)tetrahydro-2H-pyran-4-carbonitrile; 4-Cyano-4-(tosyloxymethyl)tetrahydropyran; 4-(Tosyloxymethyl)tetrahydro-2H-pyran-4-carbonitrile
EINECS	Contact for details

Quality Control

Our (4-Cyanotetrahydro-2H-Pyran-4-Yl)Methyl 4-Methylbenzenesulfonate is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to quality supports your R&D and scale-up processes with reliable, high-purity material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.