Description

Carbamic Acid, n-[[(1S,2R)-2-(Hydroxymethyl)Cyclopropyl]Methyl]-, 1,1-Dimethylethyl Ester is a high-purity, stereochemically defined carbamate derivative, serving as a critical chiral building block in advanced organic synthesis. Its value lies in the unique cyclopropylmethyl-hydroxymethyl scaffold, which provides a rigid, three-dimensional structure for constructing complex bioactive molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients where precise stereochemistry is paramount for efficacy.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, especially in protease inhibitor and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the construction of advanced, stereoselective pesticides and herbicides with improved environmental profiles.
• Chemical Biology Probe Development: Serves as a versatile scaffold for creating molecular probes to study enzyme mechanisms and biological pathways.
• Peptidomimetics Research: The carbamate and cyclopropyl groups are valuable for designing stable peptide analogs with enhanced metabolic stability.
• Asymmetric Catalysis Ligand Precursor: Potential use in the synthesis of novel chiral ligands for asymmetric hydrogenation and other catalytic transformations.
• Material Science Monomer: Can be investigated as a specialty monomer for polymers requiring specific rigidity and functionality.

Basic Information

Product Name	Carbamic Acid, n-[[(1S,2R)-2-(Hydroxymethyl)Cyclopropyl]Methyl]-, 1,1-Dimethylethyl Ester
CAS No.	1932444-00-2
Molecular Formula	C11H21NO3
Molecular Weight	215.29 g/mol
Synonyms	tert-Butyl N-[[(1S,2R)-2-(hydroxymethyl)cyclopropyl]methyl]carbamate; (1S,2R)-2-[[(tert-Butoxycarbonyl)amino]methyl]cyclopropanemethanol; BOC-Cyclopropylmethylamine Alcohol Derivative; (1S,2R)-N-Boc-2-(Aminomethyl)cyclopropanemethanol; (1S,2R)-2-((tert-Butoxycarbonylamino)methyl)cyclopropylmethanol; (1S,2R)-2-(((tert-Butoxycarbonyl)amino)methyl)cyclopropane-1-methanol; BOC-Protected (1S,2R)-2-(Aminomethyl)cyclopropanemethanol; BOC-Amino Cyclopropane Methanol Derivative
EINECS	Contact for details

Quality Control

Our Carbamic Acid, n-[[(1S,2R)-2-(Hydroxymethyl)Cyclopropyl]Methyl]-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC to ensure stereochemical purity and identity confirmation by NMR and mass spectrometry. We provide detailed Certificates of Analysis (COA) with every shipment, documenting purity, enantiomeric excess, and impurity profiles to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Store away from incompatible materials such as strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.