Description

(1S,5R,7R)-2-Oxabicyclo[3.2.0]Heptan-7-Amine is a high-purity, stereochemically defined bicyclic amine building block of significant interest in advanced organic synthesis. This compound matters as a key chiral intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and other therapeutic areas requiring rigid, three-dimensional scaffolds.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, particularly in neuroscience and antiviral research.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies to explore and optimize the biological activity of lead compounds.
• Asymmetric Synthesis: Serves as a versatile building block for constructing complex, stereochemically rich molecules via ring-opening or functional group transformations.
• Process Chemistry: Investigated for scalable routes in the development of commercial Active Pharmaceutical Ingredients (APIs).
• Chemical Biology: Potential use as a molecular probe or linker due to its reactive amine functionality and constrained geometry.
• Academic Research: Employed in methodological studies for new synthetic transformations involving strained heterocyclic systems.

Basic Information

Product Name	(1S,5R,7R)-2-Oxabicyclo[3.2.0]Heptan-7-Amine
CAS No.	1932429-35-0
Molecular Formula	C6H11NO
Molecular Weight	113.16 g/mol
Synonyms	(1S,5R,7R)-7-Amino-2-oxabicyclo[3.2.0]heptane; (7R)-2-Oxabicyclo[3.2.0]heptan-7-amine, (1S,5R)-; endo-(1S,5R,7R)-2-Oxabicyclo[3.2.0]heptan-7-amine; Bicyclo[3.2.0]heptan-7-amine, 2-oxa-, (1S,5R,7R)-; CAS 1932429-35-0
EINECS	Contact for details

Quality Control

Every batch of (1S,5R,7R)-2-Oxabicyclo[3.2.0]Heptan-7-Amine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including chiral HPLC and NMR, to ensure high stereochemical purity and chemical identity. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). For long-term storage, consider keeping the material under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.