Description

Cyclopropanecarboxylic Acid,2-Iodo-,(1S,2S)- CAS NO 1932315-23-5 is a high-purity, chiral iodinated cyclopropane derivative, a crucial building block in modern organic synthesis. This compound is valued for its unique stereochemistry and reactive iodine substituent, enabling the construction of complex, three-dimensional molecular architectures. It is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, infectious diseases, and oncology.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, where the cyclopropane ring can impart metabolic stability and unique biological activity.
• Asymmetric Synthesis: Serves as a versatile precursor in stereoselective cross-coupling reactions (e.g., Suzuki, Negishi) and cycloadditions to introduce the chiral cyclopropane motif.
• Ligand and Catalyst Development: Employed in the preparation of specialized chiral ligands and organocatalysts for enantioselective transformations.
• Material Science Precursor: Can be utilized in the synthesis of advanced organic materials and liquid crystals, where its rigid, chiral structure is beneficial.
• Chemical Biology Probes: Acts as a scaffold for creating molecular probes to study enzyme mechanisms and biological pathways due to its potential for further functionalization.

Basic Information

Product Name	Cyclopropanecarboxylic Acid,2-Iodo-,(1S,2S)-
CAS No.	1932315-23-5
Molecular Formula	C4H5IO2
Molecular Weight	211.99 g/mol
Synonyms	(1S,2S)-2-Iodocyclopropanecarboxylic Acid; (1S,2S)-2-Iodocyclopropane-1-carboxylic Acid; (1S-cis)-2-Iodocyclopropanecarboxylic Acid; trans-(1S,2S)-2-Iodocyclopropanecarboxylic Acid; Iodocyclopropanecarboxylic Acid (S,S-isomer); Chiral 2-Iodocyclopropanecarboxylic Acid; (1S,2S)-rel-2-Iodocyclopropanecarboxylic Acid
EINECS	Contact for details

Quality Control

Every batch of (1S,2S)-2-Iodocyclopropanecarboxylic Acid is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We provide full traceability and Certificates of Analysis (COA) confirming identity, purity, and enantiomeric excess. Our standard quality commitment aligns with the requirements for advanced pharmaceutical intermediates, ensuring reliable and reproducible performance in your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is between 2°C and 8°C for long-term stability. Allow the container to reach room temperature before opening to minimize moisture condensation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.