Description

(R)-[1,4]Dioxane-2-Carboxylic Acid CAS NO 1932281-42-9 is a high-value chiral building block featuring a dioxane ring fused with a carboxylic acid functional group. This compound is critical for the synthesis of complex molecules where stereochemical control is paramount, offering a unique scaffold for pharmaceutical and advanced material research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Asymmetric Catalyst Ligand Precursor: Serves as a starting material for synthesizing sophisticated chiral ligands used in enantioselective catalysis.
• Agrochemical Research: Used in the discovery and synthesis of new, stereochemically pure herbicides, fungicides, and plant growth regulators.
• Material Science: Employed in the development of chiral polymers, liquid crystals, and other advanced functional materials with specific optical properties.
• Academic & Contract Research: A valuable reagent for methodological studies in organic synthesis and medicinal chemistry within university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	(R)-[1,4]Dioxane-2-Carboxylic Acid
CAS No.	1932281-42-9
Molecular Formula	C5H8O4
Molecular Weight	132.11 g/mol
Synonyms	(R)-1,4-Dioxane-2-carboxylic acid; (R)-2-Carboxy-1,4-dioxane; (2R)-1,4-Dioxane-2-carboxylic acid; (R)-Dioxan-2-carboxylic acid; (R)-Tetrahydro-1,4-dioxin-2-carboxylic acid; (R)-2,3-Dihydro-1,4-dioxine-2-carboxylic acid; (R)-Glycidic acid 1,4-dioxane derivative
EINECS	Contact for details

Quality Control

Every batch of (R)-[1,4]Dioxane-2-Carboxylic Acid is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity (typically ≥97% by HPLC), enantiomeric excess (ee), and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its acidic nature and sensitivity, the container should be kept away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.