Description

(3S,4R)-3-Fluorooxan-4-Ol CAS NO 1932230-57-3 is a high-purity chiral fluorinated building block, a key intermediate in modern synthetic organic chemistry. Its defined stereochemistry and fluorine substitution make it a valuable synthon for constructing complex molecules with enhanced biological activity and metabolic stability. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for the development of new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel Active Pharmaceutical Ingredients (APIs), especially in fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the fluorine atom can improve lipophilicity, membrane permeability, and overall efficacy.
• Asymmetric Catalysis & Ligand Development: Serves as a precursor for chiral ligands and catalysts used in enantioselective synthesis, enabling the production of single-isomer compounds.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials where fluorination can alter physical properties like thermal stability and chemical resistance.
• Process Chemistry & Scale-up: Provides a reliable, high-quality starting material for route scouting, optimization, and commercial-scale manufacturing of fine chemicals.

Basic Information

Product Name	(3S,4R)-3-Fluorooxan-4-Ol
CAS No.	1932230-57-3
Molecular Formula	C5H9FO2
Molecular Weight	120.12 g/mol
Synonyms	(3S,4R)-3-Fluorotetrahydro-2H-pyran-4-ol; (3S,4R)-3-Fluoro-4-hydroxytetrahydropyran; 3-Fluorooxan-4-ol (3S,4R)-; Tetrahydro-2H-pyran-4-ol, 3-fluoro-, (3S,4R)-; Fluorinated tetrahydropyranol; Chiral fluorinated pyranol
EINECS	Contact for details

Quality Control

Every batch of (3S,4R)-3-Fluorooxan-4-Ol is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and enantiomeric excess meet the stringent requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA) including results for assay, chiral purity (HPLC), and impurity profile is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.