Description

(1S,5R,7S)-2-Oxabicyclo[3.2.0]Heptan-7-Amine is a high-purity, stereochemically defined bicyclic amine building block of significant interest in advanced organic synthesis. This compound matters as a key chiral intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for applications such as the synthesis of novel active pharmaceutical ingredients (APIs) and other biologically active compounds.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new therapeutic agents, including potential antiviral, antibacterial, or central nervous system (CNS) drugs.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization to introduce specific stereochemistry and functional groups into candidate molecules.
• Process Chemistry: Serves as a starting material or advanced intermediate in the scalable synthesis of complex target molecules under Good Manufacturing Practice (GMP) conditions.
• Agrochemical Research: Employed in the synthesis of novel, stereospecific pesticides or herbicides where the biological activity is highly dependent on molecular configuration.
• Asymmetric Synthesis: Acts as a chiral auxiliary or building block in catalytic asymmetric reactions to construct other enantiomerically pure compounds.
• Chemical Biology: Utilized as a probe or linker in the development of chemical tools for studying biological pathways and protein interactions.

Basic Information

Product Name	(1S,5R,7S)-2-Oxabicyclo[3.2.0]Heptan-7-Amine
CAS No.	1932196-89-8
Molecular Formula	C6H11NO
Molecular Weight	113.16 g/mol
Synonyms	(1S,5R,7S)-7-Amino-2-oxabicyclo[3.2.0]heptane; 2-Oxabicyclo[3.2.0]heptan-7-amine, (1S,5R,7S)-; (1S,5R,7S)-7-Amino-2-oxabicyclo[3.2.0]heptane; (1S,5R,7S)-2-Oxabicyclo[3.2.0]heptan-7-ylamine; 2-Oxabicyclo[3.2.0]heptan-7-amine, (1S,5R,7S)-rel-; Bicyclo[3.2.0]heptan-7-amine, 2-oxa-, (1S,5R,7S)-
EINECS	Contact for details

Quality Control

Our (1S,5R,7S)-2-Oxabicyclo[3.2.0]Heptan-7-Amine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) and spectroscopic confirmation (NMR, MS) are provided to guarantee identity, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.