Description

tert-Butyl ((3R,4R)-3-Hydroxytetrahydro-2H-Pyran-4-Yl)Carbamate is a high-purity chiral building block and advanced pharmaceutical intermediate. This compound is critical for the synthesis of complex molecules, offering precise stereochemical control for the development of active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutics, particularly in areas requiring sophisticated carbohydrate or heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of novel drug candidates, particularly for antiviral, anticancer, or neurological therapies.
• Protease Inhibitor Synthesis: Serves as a crucial precursor in the construction of complex molecular scaffolds for protease inhibitor development.
• Carbohydrate Mimetic Chemistry: Used in the research and production of glycomimetics and other sugar-based therapeutic agents.
• Asymmetric Synthesis: Employed as a building block in stereoselective reactions to introduce defined chiral centers into target molecules.
• Chemical Biology Research: Utilized in the design and synthesis of molecular probes and tool compounds for biological pathway investigation.
• Process Chemistry Development: Serves as a reference standard and starting material for scaling up synthetic routes under GMP conditions.

Basic Information

Product Name	tert-Butyl ((3R,4R)-3-Hydroxytetrahydro-2H-Pyran-4-Yl)Carbamate
CAS No.	1931934-93-8
Molecular Formula	C10H19NO4
Molecular Weight	217.26 g/mol
Synonyms	(3R,4R)-4-[(tert-Butoxycarbonyl)amino]tetrahydro-2H-pyran-3-ol; tert-Butyl N-[(3R,4R)-3-hydroxytetrahydro-2H-pyran-4-yl]carbamate; Boc-(3R,4R)-3-Hydroxypiperidine-4-carboxylic Acid Derivative (related); (3R,4R)-3-Hydroxy-4-(Boc-amino)tetrahydropyran; BOC-Protected Amino Tetrahydropyranol; Chiral Boc-Amino Alcohol Intermediate; 1931934-93-8
EINECS	Contact for details

Quality Control

Our tert-Butyl ((3R,4R)-3-Hydroxytetrahydro-2H-Pyran-4-Yl)Carbamate is manufactured under strict quality management systems. The product undergoes rigorous analytical testing, including chiral HPLC, to ensure high chemical and enantiomeric purity suitable for pharmaceutical research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every batch and provided upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.