Description

2-Bromo-4-(Methoxymethyl)-1-Methylbenzene is a high-purity, specialized brominated aromatic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both bromine and a methoxymethyl substituent, makes it a versatile intermediate for constructing complex molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting new small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of novel pesticides, herbicides, and fungicides, where the bromine atom offers a handle for further functionalization.
• Ligand and Catalyst Development: Acts as a starting material for the preparation of specialized ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, liquid crystals, and advanced polymers requiring specific aromatic architectures.
• Cross-Coupling Reactions: The bromine substituent makes it a suitable substrate for palladium-catalyzed cross-coupling reactions, such as Suzuki, Negishi, and Buchwald-Hartwig aminations.
• Chemical Biology Probes: Useful for synthesizing tagged molecules or probes for studying biological mechanisms and pathways.

Basic Information

Product Name	2-Bromo-4-(Methoxymethyl)-1-Methylbenzene
CAS No.	1897510-17-6
Molecular Formula	C9H11BrO
Molecular Weight	215.09 g/mol
Synonyms	1-Bromo-2-(methoxymethyl)-5-methylbenzene; 2-Bromo-4-(methoxymethyl)toluene; 4-(Methoxymethyl)-2-bromotoluene; 2-Bromo-α-methyl-p-tolyl methyl ether; Benzene, 2-bromo-4-(methoxymethyl)-1-methyl-; 2-Bromo-4-methoxymethyl-1-methylbenzene
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-(Methoxymethyl)-1-Methylbenzene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.