Description

2,5-Diethynyl-1,4-Benzenedicarboxaldehyde CAS NO 1888397-10-1 is a highly functionalized aromatic dialdehyde building block featuring two terminal alkyne groups. This unique molecular architecture makes it a critical precursor for constructing advanced organic frameworks, such as covalent organic frameworks (COFs) and metal-organic frameworks (MOFs), through dynamic covalent chemistry. It is essential for researchers and manufacturers in advanced materials science, organic electronics, and pharmaceutical chemistry who require a versatile and reactive linker molecule for synthesizing complex, porous, and functional materials.

Application

• Covalent Organic Framework (COF) Synthesis: Serves as a key linear linker with aldehyde and alkyne functionalities for constructing 2D and 3D porous crystalline polymers.
• Metal-Organic Framework (MOF) Precursor: Used to create functionalized ligands that can coordinate with metal ions to form hybrid materials with tailored porosity and reactivity.
• Click Chemistry Substrate: The terminal alkynes are ideal for copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions to attach diverse functional modules.
• Polymer and Dendrimer Chemistry: Acts as a core monomer for the synthesis of hyperbranched polymers and dendrimers with aldehyde groups for further modification.
• Organic Electronic Materials: Employed in the development of conjugated polymers and small molecules for applications in organic light-emitting diodes (OLEDs) and semiconductors.
• Pharmaceutical Intermediate: Utilized in the research and development of complex drug molecules and bioactive compounds requiring precise molecular scaffolding.
• Sensor Development: Incorporated into the matrix of chemical sensors and probes where its reactive sites can be functionalized to detect specific analytes.
• Surface Functionalization: Used to modify material surfaces (e.g., nanoparticles, electrodes) with aldehyde and alkyne groups for subsequent immobilization of biomolecules or catalysts.

Basic Information

Item	Details
Product Name	2,5-Diethynyl-1,4-Benzenedicarboxaldehyde
CAS No.	1888397-10-1
Molecular Formula	C12H6O2
Molecular Weight	182.18 g/mol
Synonyms	1,4-Benzenedicarboxaldehyde, 2,5-diethynyl-; 2,5-Diethynylterephthalaldehyde; Terephthalaldehyde, 2,5-diethynyl-; 2,5-Bis(ethynyl)terephthalaldehyde; 2,5-Diethynylbenzene-1,4-dicarbaldehyde
EINECS	Contact for details

Quality Control

Our 2,5-Diethynyl-1,4-Benzenedicarboxaldehyde is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FT-IR, to ensure high purity and consistent chemical identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your R&D and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive (store away from light). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown powder or crystals
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Assay	≥ 90% (by titration)
Melting Point	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.