Description

Idt-C6-2Cho is a high-purity, specialized chemical intermediate designed for advanced synthesis. This compound is critical for researchers and manufacturers requiring precise molecular building blocks for complex organic and pharmaceutical chemistry. It is primarily utilized in the development of oligonucleotides, active pharmaceutical ingredients (APIs), and other fine chemicals where structural integrity and purity are paramount.

Application

• Oligonucleotide Synthesis: A key phosphoramidite or protected nucleoside intermediate for solid-phase synthesis of DNA/RNA strands.
• Pharmaceutical R&D: Used in the research and development of novel therapeutic agents, including antisense oligonucleotides and small molecule drugs.
• Prodrug Development: Serves as a functionalized linker or protecting group in the design of prodrugs to enhance bioavailability.
• Bioconjugation: Employed to attach reporter molecules, labels, or other functional groups to biomolecules for diagnostic applications.
• Chemical Biology: A valuable tool for studying nucleic acid structure, function, and interactions within biological systems.
• Fine Chemical Manufacturing: Acts as a sophisticated intermediate in multi-step synthetic routes for high-value specialty chemicals.

Basic Information

Product Name	Idt-C6-2Cho
CAS No.	1883441-93-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	2'-O-(2-Cyanoethoxy)methyl-5'-O-(4,4'-dimethoxytrityl)-N2-isobutyryl-2'-deoxyguanosine, 3'-[(2-Cyanoethyl)-N,N-diisopropylphosphoramidite]; 5'-O-DMT-2'-O-(2-cyanoethoxymethyl)-N2-isobutyryl-2'-deoxyguanosine, 3'-(2-cyanoethyl diisopropylphosphoramidite); Idt-dG-CE Phosphoramidite; 2'-O-MOE-5-methyluridine Phosphoramidite (related class); Protected Deoxyguanosine Phosphoramidite; dG-CEM Phosphoramidite
EINECS	Contact for details

Quality Control

Every batch of Idt-C6-2Cho is manufactured and tested under strict quality management systems to ensure exceptional purity and consistency for sensitive applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed specifications for identity, purity, and related substances are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store the product in a freezer at -20°C ± 5°C under an inert atmosphere (e.g., argon or nitrogen) due to its sensitivity to oxidation and moisture. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid or foam
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in anhydrous acetonitrile, DMF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.