Description

2H-Pyran-4-Propanoic Acid, α-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]Tetrahydro-, (αr)- is a specialized, high-purity chemical building block designed for advanced synthetic applications. This compound is critical for researchers and manufacturers requiring precise molecular architecture, particularly in the development of novel active pharmaceutical ingredients (APIs) and complex organic molecules. It is primarily utilized by the pharmaceutical, biotechnology, and advanced materials sectors for peptide synthesis, medicinal chemistry, and as a key chiral intermediate.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis, often as a protected amino acid derivative.
• Medicinal Chemistry & Drug Discovery: Serves as a crucial scaffold for structure-activity relationship (SAR) studies and library development.
• Bioconjugation: Employed in the development of antibody-drug conjugates (ADCs) and other targeted therapeutic agents.
• Organic Synthesis Research: A valuable reagent for academic and industrial research in developing new synthetic methodologies.
• Advanced Materials: Potential use as a monomer or precursor in the synthesis of specialized polymers with unique properties.

Basic Information

Product Name	2H-Pyran-4-Propanoic Acid, α-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]Tetrahydro-, (αr)-
CAS No.	1879080-16-6
Molecular Formula	C23H25NO5
Molecular Weight	395.45 g/mol
Synonyms	(αR)-α-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]tetrahydro-2H-pyran-4-propanoic acid; Fmoc-(R)-Amino Acid Derivative; Fmoc-protected tetrahydro-2H-pyran amino acid; (R)-3-(Tetrahydro-2H-pyran-4-yl)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)propanoic acid; CAS 1879080-16-6; Chiral Fmoc-Amino Acid; 4-Propanoic Acid, 2H-Pyran-, α-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]tetrahydro-, (αR)-
EINECS	Contact for details

Quality Control

Our production of 2H-Pyran-4-Propanoic Acid, α-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]Tetrahydro-, (αr)- adheres to stringent quality protocols suitable for pharmaceutical R&D and cGMP applications. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure high chemical and isomeric purity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions, preferably in a controlled atmosphere, to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.