Description

2-Amino-4-Bromo-5-Hydroxy-Benzoic Acid is a halogenated aminohydroxybenzoic acid derivative that serves as a versatile and high-value synthetic intermediate. Its unique substitution pattern makes it a critical building block for the development of complex organic molecules, particularly in advanced pharmaceutical research. This compound is essential for chemists and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific bromine and amino functionalities into target structures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially for drug discovery programs targeting specific receptor sites.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators where its bromine atom is utilized for further functionalization.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed coupling reactions and other catalytic processes.
• Dye and Pigment Chemistry: Acts as an intermediate in the production of specialized azo dyes and high-performance pigments due to its amino and hydroxy groups.
• Material Science Research: Employed in the synthesis of organic semiconductors, metal-organic frameworks (MOFs), and other advanced functional materials.
• Bioconjugation and Probe Synthesis: Useful for creating fluorescent probes or affinity tags for biochemical and diagnostic applications.

Basic Information

Product Name	2-Amino-4-Bromo-5-Hydroxy-Benzoic Acid
CAS No.	1862525-85-6
Molecular Formula	C7H6BrNO3
Molecular Weight	232.03 g/mol
Synonyms	5-Hydroxy-2-amino-4-bromobenzoic acid; 4-Bromo-5-hydroxyanthranilic acid; 2-Amino-4-bromo-5-hydroxybenzoic acid; Benzoic acid, 2-amino-4-bromo-5-hydroxy-; 4-Bromo-5-hydroxy-2-aminobenzoic acid; 1862525-85-6
EINECS	Contact for details

Quality Control

Our production of 2-Amino-4-Bromo-5-Hydroxy-Benzoic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, and we support custom purity grades to meet specific research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.