Description

2,3-Dihydro-1-Benzofuran-5-Sulfinate CAS NO 1859988-99-0 is a specialized organic sulfinate derivative of the benzofuran class, serving as a valuable synthetic intermediate and building block in advanced chemical synthesis. Its significance lies in its unique sulfinate functional group, which enables versatile reactivity for the introduction of sulfur-containing motifs into target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders or requiring benzofuran scaffolds.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the sulfinate group for structure-activity relationship (SAR) studies.
• Organic Ligand Precursor: Serves as a precursor for the preparation of specialized ligands used in catalysis and coordination chemistry.
• Material Science Research: Employed in the development of organic electronic materials, such as semiconductors or light-emitting materials, where the benzofuran core is advantageous.
• Cross-Coupling Reactions: Acts as a sulfinate-based coupling partner in transition metal-catalyzed reactions, such as sulfonylation processes, to form C-S bonds.
• Chemical Biology Probes: Utilized in the design and synthesis of chemical probes for studying biological pathways and protein functions.

Basic Information

Product Name	2,3-Dihydro-1-Benzofuran-5-Sulfinate
CAS No.	1859988-99-0
Molecular Formula	C8H7O3S- (typically as a salt, e.g., sodium salt)
Molecular Weight	183.20 g/mol (Free acid, theoretical)
Synonyms	5-Sulfino-2,3-dihydrobenzofuran; 2,3-Dihydrobenzofuran-5-sulfinic acid; Benzofuran-5-sulfinate, 2,3-dihydro-; 2,3-Dihydro-1-benzofuran-5-sulfinic acid; Dihydrobenzofuransulfinate; 5-(Sulfino)-2,3-dihydrobenzofuran; 2,3-Dihydrobenzo[b]furan-5-sulfinate
EINECS	Contact for details

Quality Control

Our 2,3-Dihydro-1-Benzofuran-5-Sulfinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and process development. Certificates of Analysis (COA) with detailed batch-specific data are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95% (Research Grade)
Water Content (KF)	≤2.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.