Description

4-(4-Isopropylphenyl)-5-Tetrahydro-2H-Pyran-4-Yl-4H-1,2,4-Triazole-3-Thiol is a high-purity, specialized heterocyclic compound featuring a triazole-thiol core functionalized with isopropylphenyl and tetrahydropyranyl groups. This molecular architecture makes it a critical intermediate and building block for advanced research and development in medicinal chemistry and agrochemical synthesis. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, or infectious diseases.
• Agrochemical Research: Serves as a core scaffold for developing new-generation fungicides, herbicides, or plant growth regulators with enhanced efficacy.
• Ligand & Catalyst Development: Utilized in organometallic chemistry and catalysis research due to its potential as a chelating agent or ligand for metal complexes.
• Material Science: Investigated as a monomer or additive for creating specialty polymers with unique thermal or chemical resistance properties.
• Chemical Biology Probe: Used in biochemical research to study enzyme inhibition or protein-ligand interactions, leveraging its reactive thiol and triazole functionalities.

Basic Information

Item	Detail
Product Name	4-(4-Isopropylphenyl)-5-Tetrahydro-2H-Pyran-4-Yl-4H-1,2,4-Triazole-3-Thiol
CAS No.	1858251-43-0
Molecular Formula	C16H21N3OS
Molecular Weight	303.42 g/mol
Synonyms	5-(Tetrahydro-2H-pyran-4-yl)-4-(4-isopropylphenyl)-4H-1,2,4-triazole-3-thiol; 4-(4-Isopropylphenyl)-5-(tetrahydro-2H-pyran-4-yl)-1,2,4-triazole-3-thiol; 4-(4-Isopropylphenyl)-5-(tetrahydropyran-4-yl)-4H-1,2,4-triazole-3-thiol; 1,2,4-Triazole-3-thiol, 4-(4-isopropylphenyl)-5-(tetrahydro-2H-pyran-4-yl)-; THP-Triazole Thiol Derivative; Isopropylphenyl-THP-triazolethiol
EINECS	Contact for details

Quality Control

Our production of 4-(4-Isopropylphenyl)-5-Tetrahydro-2H-Pyran-4-Yl-4H-1,2,4-Triazole-3-Thiol adheres to stringent quality protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets exacting R&D and process chemistry standards. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider keeping under an inert atmosphere (nitrogen or argon) to maintain stability and purity. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.