Description

2,5-Dibromobenzo[B]Furan-3(2H)-One is a high-purity, specialized brominated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its role as a versatile intermediate for constructing complex molecular architectures, particularly in pharmaceutical and materials science research. This compound is essential for R&D chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), agrochemicals, and functional organic materials. The product, identified by CAS number 1823918-46-2, is supplied with stringent quality control to ensure batch-to-batch consistency for critical applications.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly those with brominated furan or benzofuran scaffolds.
• Agrochemical Synthesis: Used in the preparation of advanced crop protection agents and herbicides where the dibrominated structure imparts specific biological activity.
• Organic Light-Emitting Diode (OLED) Materials: Acts as a precursor for electron-transport or host materials in the development of next-generation display and lighting technologies.
• Ligand and Catalyst Development: Employed in the synthesis of novel ligands for transition metal catalysis or as a building block for organocatalysts.
• Polymer and Material Science: Utilized to introduce bromine functional groups into polymers or small molecules to modify physical properties like flame retardancy or reactivity.
• Academic and Industrial Research: A valuable reagent for methodological studies in organic chemistry, including cross-coupling reactions and heterocyclic chemistry.

Basic Information

Item	Detail
Product Name	2,5-Dibromobenzo[B]Furan-3(2H)-One
CAS No.	1823918-46-2
Molecular Formula	C8H4Br2O2
Molecular Weight	291.93 g/mol
Synonyms	2,5-Dibromo-3-hydroxybenzofuran; 2,5-Dibromobenzofuran-3-ol; 3-Hydroxy-2,5-dibromobenzofuran; 2,5-Dibromo-3-oxo-2,3-dihydrobenzofuran; 2,5-Dibromo-3(2H)-benzofuranone; 2,5-Dibromophthalide (incorrect but common misnomer search term); 2,5-Dibromo-1-benzofuran-3-one
EINECS	Contact for details

Quality Control

Every batch of 2,5-Dibromobenzo[B]Furan-3(2H)-One is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for research and scale-up. A detailed Certificate of Analysis (COA) is available for each lot, confirming identity, purity, and impurity profiles. Our quality commitment supports compliance with relevant research and development guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. Due to its light-sensitive nature, containers should be amber glass or opaque to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.