Description

Potassium (1-Boc-4-Piperidinylmethoxyoxy)Methyltrifluoroborate is a high-value organotrifluoroborate reagent, a crucial building block in modern synthetic chemistry. This compound is specifically engineered to facilitate robust and selective cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is an essential intermediate for pharmaceutical R&D, agrochemical synthesis, and advanced material science, where precision and reliability are paramount.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key boron-based coupling partner for the synthesis of biaryl and heterobiaryl structures prevalent in active pharmaceutical ingredients (APIs).
• Pharmaceutical Intermediate Synthesis: Used in the development of novel drug candidates, particularly those containing functionalized piperidine scaffolds.
• Agrochemical Research: Employed in creating new active ingredients for crop protection with improved efficacy and selectivity.
• Material Science & OLED Development: Serves as a precursor for organic electronic materials and light-emitting compounds.
• Medicinal Chemistry & Library Synthesis: Enables rapid parallel synthesis and structure-activity relationship (SAR) studies due to its stability and reactivity.
• Process Chemistry & Scale-up: Suitable for transitioning from laboratory-scale discovery to pilot and commercial manufacturing processes.

Basic Information

Product Name	Potassium (1-Boc-4-Piperidinylmethoxyoxy)Methyltrifluoroborate
CAS No.	1823136-59-9
Molecular Formula	C13H22BF3KNO4
Molecular Weight	357.13 g/mol
Synonyms	Potassium (1-(tert-Butoxycarbonyl)-4-piperidinylmethoxyoxy)methyltrifluoroborate; Potassium Trifluoro((((1-Boc-4-piperidinyl)methoxy)oxy)methyl)borate; (1-Boc-4-Piperidinylmethoxyoxy)Methyltrifluoroborate Potassium Salt; Potassium (N-Boc-4-piperidylmethyl)oxyoxymethyltrifluoroborate; Potassium (1-Boc-piperidin-4-ylmethoxyoxy)methyltrifluoroborate; Potassium Organotrifluoroborate Reagent KB-0134; B-0134 Potassium Salt; Suzuki Coupling Reagent
EINECS	Contact for details

Quality Control

Every batch of Potassium (1-Boc-4-Piperidinylmethoxyoxy)Methyltrifluoroborate is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with the high-purity standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) providing specifications for identity, purity (by NMR & HPLC), and impurity profile is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label. This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon/nitrogen) when possible to maintain stability and purity. Keep container tightly sealed in a desiccator after opening.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Purity (NMR)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.