Description

trans-2-(o-Tolyl)Cyclopropane-1-Carboxylic Acid is a high-purity, synthetically valuable cyclopropane derivative. This compound serves as a crucial chiral building block and intermediate in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the creation of novel pesticides and herbicides, leveraging the biological activity of the cyclopropane moiety.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specific stereochemical properties.
• Academic & Process Chemistry: Employed in methodological studies and scale-up process optimization for cyclopropane-containing compounds.

Basic Information

Product Name	trans-2-(o-Tolyl)Cyclopropane-1-Carboxylic Acid
CAS No.	1821802-95-2
Molecular Formula	C11H12O2
Molecular Weight	176.21 g/mol
Synonyms	(1R,2S)-rel-2-(2-Methylphenyl)cyclopropanecarboxylic Acid; (1S,2R)-rel-2-(2-Methylphenyl)cyclopropanecarboxylic Acid; trans-2-(2-Methylphenyl)cyclopropanecarboxylic Acid; o-Tolylcyclopropanecarboxylic Acid; 2-(2-Methylphenyl)cyclopropane-1-carboxylic Acid; 2-(o-Tolyl)cyclopropanecarboxylic Acid; Cyclopropanecarboxylic acid, 2-(2-methylphenyl)-, trans-
EINECS	Contact for details

Quality Control

Every batch of trans-2-(o-Tolyl)Cyclopropane-1-Carboxylic Acid is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency, supporting your regulatory and research requirements. A detailed Certificate of Analysis (COA) including chiral purity, assay, and impurity profile is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de (trans-isomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.