Description

(S)-1,4-Dioxane-2-Carboxylic Acid is a high-value chiral building block and intermediate of significant importance in advanced organic synthesis. Its enantiomerically pure structure makes it a critical precursor for the development of novel pharmaceuticals and fine chemicals. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications in asymmetric synthesis and drug discovery.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of enantiomerically pure drugs.
• Asymmetric Catalyst Ligand Precursor: Used in the preparation of chiral ligands for transition metal catalysis, enabling stereoselective transformations.
• Agrochemical Synthesis: Serves as a building block for creating novel, optically active herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Employed in the synthesis of complex, high-value specialty chemicals and flavors & fragrances requiring specific stereochemistry.
• Academic & Industrial Research: A valuable tool for methodological development in organic chemistry and medicinal chemistry research programs.
• Peptidomimetics & Bioactive Molecule Design: The carboxylic acid functionality and dioxane ring make it useful for constructing conformationally constrained analogs of peptides and other bioactive compounds.

Basic Information

Product Name	(S)-1,4-Dioxane-2-Carboxylic Acid
CAS No.	1821739-82-5
Molecular Formula	C5H8O4
Molecular Weight	132.11 g/mol
Synonyms	(S)-(+)-1,4-Dioxane-2-carboxylic acid; (S)-1,4-Dioxane-2-carboxylic acid; (2S)-1,4-Dioxane-2-carboxylic acid; (S)-2-Carboxy-1,4-dioxane; 1,4-Dioxane-2-carboxylic acid, (S)-; (S)-Dioxanecarboxylic acid
EINECS	Contact for details

Quality Control

Our (S)-1,4-Dioxane-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical and enantiomeric purity, meeting the stringent requirements of research and production applications. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (enantiomeric excess), and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider holding under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% e.e.
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.