Description

3-(Pyridazin-3-Yloxy)-8-Azabicyclo[3.2.1]Octane Dihydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS number 1820740-02-0. This compound is valued for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and other therapeutic areas. It is primarily utilized by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates targeting specific biological pathways.
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization programs.
• Process Chemistry Development: Serves as a standard for scaling up synthetic routes from laboratory to pilot and commercial production.
• Reference Standard: Employed as an analytical standard for method development, validation, and quality control of final APIs.
• Biochemical Research: Potential use as a tool compound for probing enzyme inhibition or receptor binding studies in vitro.
• Custom Synthesis: Basis for the custom manufacturing of derivatives and analogs for specialized client projects.

Basic Information

Product Name	3-(Pyridazin-3-Yloxy)-8-Azabicyclo[3.2.1]Octane Dihydrochloride
CAS No.	1820740-02-0
Molecular Formula	C11H16Cl2N2O
Molecular Weight	263.16 g/mol
Synonyms	8-Azabicyclo[3.2.1]octane, 3-(3-pyridazinyloxy)-, dihydrochloride; 3-(Pyridazin-3-yloxy)-8-azabicyclo[3.2.1]octane hydrochloride (1:2); 3-Pyridazin-3-yloxy-8-azabicyclo[3.2.1]octane dihydrochloride; 8-Azabicyclo[3.2.1]octan-3-ol, 3-(3-pyridazinyloxy)-, dihydrochloride; Bicyclo[3.2.1]octane-3-ol, 8-aza-3-(3-pyridazinyloxy)-, dihydrochloride
EINECS	Contact for details

Quality Control

Our 3-(Pyridazin-3-Yloxy)-8-Azabicyclo[3.2.1]Octane Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under anhydrous conditions to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.