Description

(R)-8-Bromochroman-4-Amine Hydrochloride is a chiral building block of significant importance in modern organic synthesis and pharmaceutical research. Its value lies in its role as a key intermediate for constructing complex molecules with defined stereochemistry, which is critical for developing active pharmaceutical ingredients (APIs) and other fine chemicals. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries focused on developing new therapeutic agents and high-value chemical entities.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and development of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Used in the synthesis of advanced, stereoselective pesticides and herbicides where specific chirality impacts biological activity.
• Asymmetric Catalysis Research: Serves as a ligand precursor or a chiral scaffold in the development of new catalytic systems for stereoselective transformations.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Material Science Research: Potential building block for creating chiral polymers or advanced organic materials with specific optical properties.
• Academic & Contract Research: Essential for academic laboratories and CROs (Contract Research Organizations) conducting method development and synthetic chemistry studies.

Basic Information

Product Name	(R)-8-Bromochroman-4-Amine Hydrochloride
CAS No.	1810074-69-1
Molecular Formula	C9H11BrClNO
Molecular Weight	264.55 g/mol
Synonyms	(R)-8-Bromo-3,4-dihydro-2H-1-benzopyran-4-amine hydrochloride; (4R)-8-Bromo-3,4-dihydro-2H-chromen-4-amine hydrochloride; (R)-8-Bromo-3,4-dihydro-2H-chromen-4-amine HCl; 8-Bromochroman-4-amine hydrochloride, (R)-; (R)-8-Bromochroman-4-amine HCl; (R)-4-Amino-8-bromochroman hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-8-Bromochroman-4-Amine Hydrochloride is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for research and development applications. Each lot undergoes comprehensive analytical characterization, including chiral purity verification by HPLC. A detailed Certificate of Analysis (COA) providing specifications for identity, purity, and related substances is available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0%
Chiral Purity (Chiral HPLC)	≥98.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.