Description

(S)-8-Bromochroman-4-Amine Hydrochloride CAS NO 1810074-67-9 is a high-purity chiral building block and pharmaceutical intermediate of significant synthetic utility. Its value lies in its defined stereochemistry and functional groups, which are crucial for constructing complex molecules with specific biological activity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring chroman-based scaffolds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, especially for central nervous system (CNS) and cardiovascular targets.
• Asymmetric Synthesis: Used as a starting material or intermediate in stereoselective chemical synthesis to introduce the chroman-4-amine moiety.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization processes within drug discovery programs.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Academic Research: Utilized in universities and research institutes for methodological development in organic and medicinal chemistry.
• Precursor for Functionalized Chromans: The bromo and amine functionalities allow for further derivatization, enabling the synthesis of a diverse library of compounds.

Basic Information

Product Name	(S)-8-Bromochroman-4-Amine Hydrochloride
CAS No.	1810074-67-9
Molecular Formula	C9H11BrClNO
Molecular Weight	264.55 g/mol
Synonyms	(4S)-8-Bromo-3,4-dihydro-2H-1-benzopyran-4-amine hydrochloride; (S)-8-Bromo-3,4-dihydro-2H-chromen-4-amine hydrochloride; (S)-8-Bromo-3,4-dihydro-2H-1-benzopyran-4-amine HCl; 8-Bromo-(4S)-chroman-4-amine hydrochloride; (S)-8-Bromochroman-4-amine HCl; 1810074-67-9; (4S)-8-Bromochroman-4-amine hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-8-Bromochroman-4-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. A detailed Certificate of Analysis (COA) providing batch-specific data for identity, purity, and chiral excess is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.