Description

(4S)-8-Methyl-3,4-Dihydro-2H-1-Benzopyran-4-Amine Hydrochloride is a high-purity chiral amine derivative, a key building block in advanced pharmaceutical synthesis. Its defined stereochemistry and functionalized benzopyran scaffold make it a valuable intermediate for creating novel therapeutic agents with specific biological activity. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of central nervous system (CNS) drugs, cardiovascular agents, and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in neurological and cardiovascular therapeutic areas.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the synthesis of compound libraries for high-throughput screening.
• Asymmetric Synthesis: Used as a chiral auxiliary or precursor in catalytic asymmetric reactions to induce stereoselectivity in complex molecule construction.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes to study enzyme function and receptor-ligand interactions.
• Process Chemistry Development: Supports route scouting and optimization for the scalable, cost-effective manufacturing of candidate drugs.

Basic Information

Product Name	(4S)-8-Methyl-3,4-Dihydro-2H-1-Benzopyran-4-Amine Hydrochloride
CAS No.	1807890-95-4
Molecular Formula	C10H14ClNO
Molecular Weight	199.68 g/mol
Synonyms	(4S)-8-Methyl-3,4-dihydro-2H-chromen-4-amine hydrochloride; (4S)-8-Methyl-3,4-dihydro-2H-1-benzopyran-4-amine HCl; (S)-8-Methyl-3,4-dihydro-2H-chromen-4-amine hydrochloride; 2H-1-Benzopyran-4-amine, 3,4-dihydro-8-methyl-, (4S)-, hydrochloride; 8-Methyl-3,4-dihydro-2H-1-benzopyran-4-amine hydrochloride (S-enantiomer); (S)-8-Methylchroman-4-amine hydrochloride
EINECS	Contact for details

Quality Control

Our (4S)-8-Methyl-3,4-Dihydro-2H-1-Benzopyran-4-Amine Hydrochloride is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), chiral purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.