Description

2-Bromo-1-Chloro-3-Fluoro-4-Nitrobenzene is a high-purity halogenated nitrobenzene derivative, a crucial building block in advanced organic synthesis. Its precise molecular architecture makes it an indispensable intermediate for the development of complex pharmaceuticals, agrochemicals, and specialty materials. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel active molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing complex halogen-substituted aromatic rings.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the halogen and nitro groups confer specific biological activity.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and electronic materials.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to introduce multi-halogenated nitroaryl motifs.
• Dye and Pigment Intermediate: Acts as a starting material for synthesizing complex, color-fast azo dyes and pigments.

Basic Information

Product Name	2-Bromo-1-Chloro-3-Fluoro-4-Nitrobenzene
CAS No.	1807036-18-5
Molecular Formula	C6H2BrClFNO2
Molecular Weight	254.44 g/mol
Synonyms	1-Bromo-2-chloro-6-fluoro-3-nitrobenzene; 2-Chloro-1-bromo-3-fluoro-4-nitrobenzene; 3-Fluoro-4-nitro-1-chloro-2-bromobenzene; Benzene, 2-bromo-1-chloro-3-fluoro-4-nitro-; 4-Nitro-2-bromo-1-chloro-3-fluorobenzene; 1-Chloro-2-bromo-3-fluoro-4-nitrobenzene; BCFNB (abbreviation)
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-1-Chloro-3-Fluoro-4-Nitrobenzene is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in a dark cabinet.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%
Related Substances (HPLC)	Total impurities < 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.