Description

2-Bromo-5-Fluoro-4-(Trifluoromethoxy)Phenol is a high-purity, multi-functional halogenated phenol derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its unique structure, featuring bromine, fluorine, and trifluoromethoxy substituents, makes it an indispensable building block for introducing specific steric and electronic properties into target molecules. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides, where the halogenated phenol core enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for synthesizing fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer Modification: Acts as a functional monomer or cross-linking agent to introduce halogenated phenolic groups into specialty polymers, improving flame retardancy and chemical resistance.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitutions to construct complex, polyfunctional aromatic systems.

Basic Information

Product Name	2-Bromo-5-Fluoro-4-(Trifluoromethoxy)Phenol
CAS No.	1805939-17-6
Molecular Formula	C7H3BrF4O2
Molecular Weight	274.99 g/mol
Synonyms	2-Bromo-5-fluoro-4-(trifluoromethoxy)phenol; 4-Bromo-2-fluoro-5-(trifluoromethoxy)phenol; Phenol, 2-bromo-5-fluoro-4-(trifluoromethoxy)-; 1805939-17-6; 2-Bromo-5-fluoro-4-(trifluoromethoxy)phen-1-ol
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-5-Fluoro-4-(Trifluoromethoxy)Phenol is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber glass, or in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.