Description

2-Chloro-5-Fluoro-3-Methylphenol is a halogenated phenolic compound that serves as a versatile and high-value synthetic intermediate. Its unique substitution pattern makes it a critical building block for constructing complex molecules in advanced research and development. This compound is particularly valuable for pharmaceutical chemists and agrochemical researchers seeking to introduce specific halogenated motifs to modulate the biological activity, stability, and physicochemical properties of target compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of novel drugs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the chloro-fluoro-methylphenol structure contributes to efficacy and environmental profile.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and advanced organic electronic materials.
• Chemical Research & Development: An essential reagent in organic synthesis for constructing complex aromatic systems, facilitating cross-coupling reactions, and as a substrate for further functional group transformations.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized halogenated dyes and pigments that require enhanced lightfastness and chemical resistance.

Basic Information

Product Name	2-Chloro-5-Fluoro-3-Methylphenol
CAS No.	1805455-85-9
Molecular Formula	C7H6ClFO
Molecular Weight	160.57 g/mol
Synonyms	2-Chloro-5-fluoro-3-methylphenol; 3-Methyl-2-chloro-5-fluorophenol; 5-Fluoro-2-chloro-3-methylphenol; Phenol, 2-chloro-5-fluoro-3-methyl-; 2-Chloro-5-fluoro-m-cresol
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-5-Fluoro-3-Methylphenol is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We provide full traceability and guarantee batch-to-batch consistency to meet the stringent requirements of pharmaceutical and agrochemical applications. A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere for long-term storage. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.