Description

3-Bromo-5-Chloro-4-(Trifluoromethyl)Aniline is a high-purity, multi-functional halogenated aniline derivative, serving as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring bromine, chlorine, and trifluoromethyl substituents, makes it an exceptionally valuable intermediate for creating complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research: Employed in academic and industrial R&D for palladium-catalyzed cross-coupling reactions (e.g., Buchwald-Hartwig amination) and as a scaffold for library synthesis in drug discovery.
• Dye and Pigment Manufacturing: Acts as an intermediate for producing complex, high-performance dyes and pigments with specific color fastness and solubility properties.

Basic Information

Product Name	3-Bromo-5-Chloro-4-(Trifluoromethyl)Aniline
CAS No.	1805186-16-6
Molecular Formula	C7H4BrClF3N
Molecular Weight	274.47 g/mol
Synonyms	3-Bromo-5-chloro-4-(trifluoromethyl)benzenamine; 4-Amino-2-bromo-6-chlorobenzotrifluoride; 2-Bromo-6-chloro-4-(trifluoromethyl)aniline; 1-Amino-3-bromo-5-chloro-4-(trifluoromethyl)benzene; Benzenamine, 3-bromo-5-chloro-4-(trifluoromethyl)-; 3-Bromo-5-chloro-alpha,alpha,α-trifluoro-p-toluidine
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Chloro-4-(Trifluoromethyl)Aniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and batch-to-batch consistency for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.