Description

2-Amino-3-Bromo-5-Fluorophenol is a halogenated aniline derivative that serves as a versatile and high-value synthetic intermediate. Its molecular structure, featuring amino, bromo, and fluoro substituents on a phenolic ring, makes it a critical building block for constructing complex molecules in advanced research and development. This compound is primarily sought after by pharmaceutical and agrochemical R&D teams for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and pesticides, leveraging the bioactivity of its halogen and amino functional groups.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers, liquid crystals, and advanced organic electronic materials.
• Dye and Pigment Intermediate: Employed in the synthesis of complex, high-performance dyes and organic pigments due to its substituted phenolic structure.
• Cross-Coupling Reactions: Acts as a valuable substrate in palladium-catalyzed cross-coupling reactions (e.g., Buchwald-Hartwig amination, Suzuki reactions) for creating biaryl structures.
• Chemical Biology & Proteomics: Utilized as a reagent for modifying proteins or synthesizing molecular probes and tags for biochemical research.

Basic Information

Product Name	2-Amino-3-Bromo-5-Fluorophenol
CAS No.	1805027-31-9
Molecular Formula	C6H5BrFNO
Molecular Weight	206.01 g/mol
Synonyms	3-Bromo-5-fluoro-2-aminophenol; 2-Amino-3-bromo-5-fluorophenol; Phenol, 2-amino-3-bromo-5-fluoro-; 5-Fluoro-3-bromo-2-aminophenol; 3-Bromo-5-fluoro-2-hydroxyaniline; 2-Hydroxy-6-bromo-4-fluoroaniline; 2-Amino-3-bromo-5-fluoro-1-hydroxybenzene
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-3-Bromo-5-Fluorophenol is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements of research and process development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and MS is supplied with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light brown crystalline powder
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.