Description

Methyl 6-Hydroxy-2,3-Dihydrobenzofuran-2-Carboxylate is a high-purity organic intermediate featuring a fused benzofuran ring system with a reactive ester and a phenolic hydroxyl group. This compound is valued for its role as a versatile synthetic building block in advanced pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the fine chemical and life sciences industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory pathways.
• Agrochemical Synthesis: Building block for developing new-generation herbicides and fungicides with enhanced efficacy and environmental profiles.
• Material Science Research: Used in the development of organic semiconductors and advanced polymers due to its rigid, planar benzofuran core.
• Chemical Biology Probes: Serves as a scaffold for creating fluorescent tags and molecular probes for enzyme and receptor studies.
• Academic & Contract Research: Essential reagent for methodological development in organic synthesis and catalysis research at universities and CROs.

Basic Information

Item	Details
Product Name	Methyl 6-Hydroxy-2,3-Dihydrobenzofuran-2-Carboxylate
CAS No.	1803591-79-8
Molecular Formula	C10H10O4
Molecular Weight	194.18 g/mol
Synonyms	6-Hydroxy-2,3-dihydrobenzofuran-2-carboxylic acid methyl ester; Methyl 6-hydroxy-2,3-dihydro-1-benzofuran-2-carboxylate; 2,3-Dihydro-6-hydroxybenzofuran-2-carboxylic acid methyl ester; 6-Hydroxy-2,3-dihydrobenzofuran-2-methyl carboxylate; 1803591-79-8; Methyl 6-hydroxy-2,3-dihydrobenzo[b]furan-2-carboxylate
EINECS	Contact for details

Quality Control

Our production of Methyl 6-Hydroxy-2,3-Dihydrobenzofuran-2-Carboxylate adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for every lot, detailing identity, purity, and impurity profiles. Our quality system is designed to support cGMP compliance for pharmaceutical applications, and we welcome audits and quality agreements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.