Description

4-(2-Bromoethynyl)-4'-(Bromoethynyl)-1,1'-Biphenyl is a high-purity, bifunctional bromoacetylene derivative of biphenyl, serving as a critical advanced intermediate in organic synthesis. Its value lies in its dual reactive sites, enabling efficient cross-coupling and polymerization reactions to construct complex molecular architectures. This compound is essential for researchers and manufacturers in the fields of pharmaceutical development, materials science (particularly for organic semiconductors and OLEDs), and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing novel active pharmaceutical ingredients (APIs), especially in kinase inhibitor and antiviral drug research.
• Organic Electronic Materials: Serves as a core monomer or precursor for conjugated polymers and small molecules used in Organic Light-Emitting Diodes (OLEDs), Organic Photovoltaics (OPVs), and Field-Effect Transistors (OFETs).
• Ligand Synthesis: Used to create sophisticated ligands for catalysis, including those for palladium-catalyzed cross-coupling reactions like Sonogashira and Suzuki couplings.
• Polymer Chemistry: Acts as a difunctional monomer for step-growth polymerization to produce rigid-rod polymers with tailored optoelectronic properties.
• Liquid Crystal & Advanced Material Research: Employed in the synthesis of novel biphenyl-based liquid crystals and other functional materials requiring a rigid, linear core with terminal reactive handles.
• Cross-Coupling Reactions: The bromoethynyl groups are excellent substrates for Sonogashira and other metal-catalyzed coupling reactions to form extended π-conjugated systems.

Basic Information

Product Name	4-(2-Bromoethynyl)-4'-(Bromoethynyl)-1,1'-Biphenyl
CAS No.	1800534-49-9
Molecular Formula	C16H8Br2
Molecular Weight	360.05 g/mol
Synonyms	1,1'-Biphenyl, 4,4'-bis(2-bromoethynyl)-; 4,4'-Bis(2-bromoethynyl)biphenyl; 4,4'-Di(2-bromoethynyl)biphenyl; 4,4'-Bis(bromoethynyl)biphenyl; Biphenyl-4,4'-diylbis(2-bromoethyne); 4,4'-(Bromoethynyl)biphenyl (ambiguous); Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our 4-(2-Bromoethynyl)-4'-(Bromoethynyl)-1,1'-Biphenyl is produced under stringent quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural integrity suitable for demanding research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged procedures to ensure stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.