Description

3-Bromo-6-Ethynylpyridazine is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. This compound matters because its unique structure, featuring both a bromine substituent and an ethynyl group on a pyridazine core, enables versatile cross-coupling and click chemistry reactions. It is primarily needed by researchers and process chemists in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex drug candidates, particularly in kinase inhibitor and CNS-active molecule research.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides by acting as a core heterocyclic scaffold.
• Material Science Precursor: Serves as a monomer or cross-linker in the synthesis of conjugated polymers and advanced organic electronic materials.
• Chemical Biology Probe Development: The ethynyl group facilitates bioorthogonal labeling (e.g., via CuAAC click chemistry) for target identification and imaging studies.
• Ligand and Catalyst Design: Utilized in organometallic chemistry to create novel chelating ligands for catalytic systems.
• Library Synthesis for HTS: A valuable building block for generating diverse compound libraries in high-throughput screening campaigns.

Basic Information

Product Name	3-Bromo-6-Ethynylpyridazine
CAS No.	1797130-79-0
Molecular Formula	C6H3BrN2
Molecular Weight	183.01 g/mol
Synonyms	6-Ethynyl-3-bromopyridazine; 3-Bromo-6-ethynyl-1,2-diazine; 3-Bromo-6-ethynylpyridazine; 1797130-79-0; 6-Ethynyl-3-bromo-1,2-diazine; Pyridazine, 3-bromo-6-ethynyl-; 3-Bromo-6-ethynylpyridazine (CAS 1797130-79-0)
EINECS	Contact for details

Quality Control

Our 3-Bromo-6-Ethynylpyridazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP standards for production, ensuring reliability for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.