Description

3-(Trifluoromethyl)Pyridazine-4-Carboxylic Acid is a high-purity fluorinated heterocyclic building block essential for advanced organic synthesis. This compound is valued for its unique chemical structure, which introduces both a carboxylic acid handle and a metabolically stable trifluoromethyl group into target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors, antiviral agents, and central nervous system (CNS) drugs.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group can enhance biological activity and environmental stability.
• Ligand & Catalyst Design: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis, useful in asymmetric synthesis.
• Material Science: Incorporated into the design of advanced organic materials, such as liquid crystals or organic semiconductors, due to its electron-withdrawing properties.
• Chemical Biology: Employed as a probe or tag in bioconjugation chemistry to study biological processes and protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	3-(Trifluoromethyl)Pyridazine-4-Carboxylic Acid
CAS No.	1792235-57-4
Molecular Formula	C6H3F3N2O2
Molecular Weight	192.10 g/mol
Synonyms	4-Pyridazinecarboxylic acid, 3-(trifluoromethyl)-; 3-Trifluoromethylpyridazine-4-carboxylic acid; 3-(Trifluoromethyl)-4-pyridazinecarboxylic acid; 1792235-57-4; 3-Trifluoromethyl-4-carboxypyridazine; 4-Carboxy-3-(trifluoromethyl)pyridazine
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethyl)Pyridazine-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.