Description

1-(2,4,6-Trimethylphenyl)-3-[(2S)-4-Methylpentanoic Acid]Imidazolium Hexafluorophosphate is a high-purity, chiral ionic liquid salt designed for advanced chemical synthesis and catalysis. This compound is valued for its role as a specialized catalyst precursor or chiral auxiliary in asymmetric synthesis, enabling the production of enantiomerically pure intermediates. It is primarily required by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and fine chemical sectors for developing novel active ingredients and high-value specialty chemicals.

Application

• Asymmetric Catalysis: As a chiral ionic liquid catalyst or catalyst precursor in stereoselective organic transformations, such as hydrogenation, cycloaddition, or cross-coupling reactions.
• Pharmaceutical Intermediate Synthesis: For the enantioselective construction of complex molecular scaffolds in the development of new active pharmaceutical ingredients (APIs).
• Agrochemical Research: In the synthesis of chiral herbicides, fungicides, and insecticides where specific stereochemistry is critical for bioactivity.
• Fine Chemical Manufacturing: For producing high-value, enantiomerically pure flavors, fragrances, and specialty materials.
• Academic & Industrial R&D: As a key reagent in methodological development and exploration of new reaction pathways in synthetic chemistry.
• Material Science: Potential use in the development of chiral ionic liquid-based electrolytes or functional materials.

Basic Information

Product Name	1-(2,4,6-Trimethylphenyl)-3-[(2S)-4-Methylpentanoic Acid]Imidazolium Hexafluorophosphate
CAS No.	1788856-37-0
Molecular Formula	C20H29F6N2O2P
Molecular Weight	498.42 g/mol
Synonyms	(S)-1-(2,4,6-Trimethylphenyl)-3-(4-methylpentanoyl)imidazolium hexafluorophosphate; (S)-1-Mesityl-3-(4-methylpentanoyl)imidazolium hexafluorophosphate; Chiral Imidazolium Hexafluorophosphate Salt; L-Leucine Derived Ionic Liquid; NHC Precursor Salt; CAS 1788856-37-0
EINECS	Contact for details

Quality Control

Our production of 1-(2,4,6-Trimethylphenyl)-3-[(2S)-4-Methylpentanoic Acid]Imidazolium Hexafluorophosphate adheres to stringent quality management protocols. Each batch is characterized and tested to ensure high chemical and enantiomeric purity, with specifications tailored to research and process development requirements. Certificates of Analysis (COA) detailing identity, purity (HPLC), chiral purity, and other critical parameters are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when appropriate to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.