Description

Methyl 3-Oxotetrahydro-2H-Pyran-4-Carboxylate is a high-purity, versatile heterocyclic building block and chiral synthon. This compound is valued for its unique lactone-keto-ester functionality, which enables its use in sophisticated multi-step synthetic pathways. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Organic Synthesis Building Block: Serves as a versatile scaffold for constructing fused ring systems, spiro compounds, and other complex heterocycles in medicinal chemistry.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in the development of new catalytic asymmetric reactions.
• Flavor & Fragrance Chemistry: Acts as an intermediate for synthesizing specific lactone-based aroma compounds.
• Material Science Research: Investigated as a monomer or cross-linking agent for specialty polymers with specific degradation profiles.

Basic Information

Product Name	Methyl 3-Oxotetrahydro-2H-Pyran-4-Carboxylate
CAS No.	1787263-94-8
Molecular Formula	C7H10O4
Molecular Weight	158.15 g/mol
Synonyms	Methyl 3-oxooxane-4-carboxylate; 4-(Methoxycarbonyl)-3-oxotetrahydro-2H-pyran; 3-Oxo-tetrahydro-2H-pyran-4-carboxylic acid methyl ester; Methyl 3-oxotetrahydropyran-4-carboxylate; 4-Carbomethoxy-3-oxotetrahydropyran; Tetrahydro-2H-pyran-4-carboxylic acid, 3-oxo-, methyl ester
EINECS	Contact for details

Quality Control

Every batch of Methyl 3-Oxotetrahydro-2H-Pyran-4-Carboxylate is manufactured under a strict quality management system and undergoes comprehensive analytical testing. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming identity, purity, and impurity profiles. Our standard grade meets the rigorous requirements for use as a pharmaceutical intermediate, with specifications tailored to customer needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.