Description

3-(Difluoromethyl)Cyclopentanone is a versatile fluorinated organic building block of significant interest in advanced chemical synthesis. Its unique structure, featuring a difluoromethyl group on a cyclopentanone ring, makes it a valuable intermediate for introducing fluorine atoms into target molecules, which can dramatically alter their physical, chemical, and biological properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting metabolic diseases and CNS disorders.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the difluoromethyl group can enhance bioavailability and environmental stability.
• Material Science Research: Serves as a precursor for fluorinated polymers and specialty materials with unique surface properties and chemical resistance.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, nucleophilic additions, and other transformations to construct complex, fluorinated molecular architectures.
• Ligand and Catalyst Development: Useful for synthesizing novel fluorinated ligands for catalysis and molecular recognition applications.

Basic Information

Product Name	3-(Difluoromethyl)Cyclopentanone
CAS No.	1780799-97-4
Molecular Formula	C6H8F2O
Molecular Weight	134.12 g/mol
Synonyms	3-(Difluoromethyl)cyclopentan-1-one; Cyclopentanone, 3-(difluoromethyl)-; 1-Cyclopentanone, 3-(difluoromethyl)-; 3-Difluoromethylcyclopentanone; 1780799-97-4
EINECS	Contact for details

Quality Control

Our 3-(Difluoromethyl)Cyclopentanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatography (GC/HPLC) and spectroscopy (NMR, IR, MS), to ensure high purity and consistent identity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, assay, and impurity profiles to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place. Due to its highly volatile nature, keep the container tightly sealed when not in use and store at recommended room temperature (15-25°C). Keep away from heat, sparks, open flames, and hot surfaces.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.