Description

2-(Chloromethyl)Cyclopropanecarboxylic Acid is a versatile and highly functionalized cyclopropane derivative, serving as a critical chiral building block in advanced organic synthesis. Its unique strained-ring structure, combined with both carboxylic acid and chloromethyl functional groups, makes it an invaluable intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of chiral drugs, particularly those targeting central nervous system (CNS) disorders, cardiovascular diseases, and antiviral therapies.
• Agrochemical Synthesis: Used to construct bioactive cyclopropane rings found in modern pesticides, herbicides, and fungicides, enhancing potency and environmental profile.
• Ligand and Catalyst Development: Serves as a scaffold for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Building block for synthesizing specialty polymers and advanced organic materials with unique mechanical or optical properties.
• Chemical Biology Probes: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and the development of molecular probes.
• Custom Synthesis & Contract Manufacturing: A high-value intermediate for custom synthesis houses serving the pharmaceutical and biotechnology industries.

Basic Information

Product Name	2-(Chloromethyl)Cyclopropanecarboxylic Acid
CAS No.	1779806-94-8
Molecular Formula	C5H7ClO2
Molecular Weight	134.56 g/mol
Synonyms	2-(Chloromethyl)cyclopropane-1-carboxylic acid; Cyclopropanecarboxylic acid, 2-(chloromethyl)-; (1R,2S)-2-(Chloromethyl)cyclopropanecarboxylic acid (for chiral forms); 2-Chloromethyl-1-cyclopropanecarboxylic acid; 1-Carboxy-2-(chloromethyl)cyclopropane; (Chloromethyl)cyclopropanecarboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 2-(Chloromethyl)Cyclopropanecarboxylic Acid is manufactured under strict quality management systems. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed results from HPLC, NMR, and GC-MS to verify identity, purity, and impurity profiles. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.