Description

1-(Cyanomethyl)Cyclobutane-1-Carboxylic Acid is a versatile cyclobutane-based building block featuring both carboxylic acid and nitrile functional groups. This bifunctional nature makes it a valuable intermediate for the synthesis of complex molecules in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the fine chemical and pharmaceutical industries for constructing novel molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting constrained ring systems.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and herbicides, leveraging its rigid cyclobutane core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of monomers and specialty polymers with unique thermal and mechanical properties.
• Chemical Biology Probes: Utilized as a building block for synthesizing molecular probes and inhibitors to study biological pathways.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring functionalized cyclobutane derivatives.

Basic Information

Product Name	1-(Cyanomethyl)Cyclobutane-1-Carboxylic Acid
CAS No.	1773507-80-4
Molecular Formula	C7H9NO2
Molecular Weight	139.15 g/mol
Synonyms	Cyclobutane-1-carboxylic acid, 1-(cyanomethyl)-; 1-(Cyanomethyl)cyclobutane-1-carboxylic acid; 1-Cyanomethyl-1-cyclobutanecarboxylic acid; 1-(Cyanomethyl)cyclobutane carboxylic acid; 1-Carboxy-1-cyclobutanemethyl cyanide; (1-Cyanomethyl-cyclobutyl)-carboxylic acid; 1-Cyanomethylcyclobutane-1-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 1-(Cyanomethyl)Cyclobutane-1-Carboxylic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties. Keep away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.