Description

(3R,4R)-3-((tert-Butoxycarbonyl)Amino)Tetrahydro-2H-Pyran-4-Yl Methanesulfonate is a high-purity chiral building block and advanced pharmaceutical intermediate. This compound is critical for the synthesis of complex, stereochemically defined active pharmaceutical ingredients (APIs), particularly in antiviral and oncology research. It is primarily utilized by pharmaceutical R&D departments and fine chemical manufacturers engaged in the production of novel therapeutics.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug molecules, especially protease inhibitors and other targeted therapies.
• Antiviral Drug Development: Serves as a crucial precursor in the research and production of next-generation antiviral agents.
• Oncology Research: Used in the construction of molecular scaffolds for potential cancer treatment candidates.
• Peptidomimetics Synthesis: Employed to introduce stereocenters and protected amino functionalities into peptide-like compounds.
• Process Chemistry & Scale-Up: Supports route scouting and optimization from laboratory to pilot and commercial manufacturing scales.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke API synthesis projects.

Basic Information

Product Name	(3R,4R)-3-((tert-Butoxycarbonyl)Amino)Tetrahydro-2H-Pyran-4-Yl Methanesulfonate
CAS No.	1707290-12-7
Molecular Formula	C12H23NO6S
Molecular Weight	309.38 g/mol
Synonyms	(3R,4R)-3-((tert-Butoxycarbonyl)amino)tetrahydro-2H-pyran-4-yl methanesulfonate; (3R,4R)-3-((Boc)amino)tetrahydro-2H-pyran-4-yl methanesulfonate; (3R,4R)-3-((tert-Butoxycarbonyl)amino)tetrahydropyran-4-yl methanesulfonate; Boc-3-amino-4-hydroxy-tetrahydropyran methanesulfonate ester; (3R,4R)-Boc-Amino-THP-Mesylate; 1707290-12-7; (3R,4R)-3-(Boc-amino)tetrahydro-2H-pyran-4-yl mesylate
EINECS	Contact for details

Quality Control

Our (3R,4R)-3-((tert-Butoxycarbonyl)Amino)Tetrahydro-2H-Pyran-4-Yl Methanesulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for pharmaceutical applications. Certificates of Analysis (COA) with detailed specifications are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.