Description

5-Chloro-2-Methyl-4-(Trifluoromethoxy)Benzenesulfonyl Chloride is a high-value, multi-functional chemical intermediate characterized by its reactive sulfonyl chloride group and trifluoromethoxy substituent. This compound is critical for introducing specific aromatic sulfonamide or sulfonate functionalities into target molecules, enabling the development of advanced materials and active ingredients. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for synthesizing novel compounds with tailored properties.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of sulfonamide-based drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethoxy group enhances biological activity and stability.
• Material Science Research: Serves as a precursor for creating specialized polymers, dyes, and liquid crystals with unique electronic or surface properties.
• Chemical Biology & Proteomics: Employed as a reactive handle for labeling or modifying biomolecules in research applications.
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical companies for use in bespoke synthesis projects and scale-up campaigns.

Basic Information

Product Name	5-Chloro-2-Methyl-4-(Trifluoromethoxy)Benzenesulfonyl Chloride
CAS No.	1706447-06-4
Molecular Formula	C9H7Cl2F3O3S
Molecular Weight	323.12 g/mol
Synonyms	4-(Trifluoromethoxy)-5-chloro-2-methylbenzenesulfonyl chloride; 5-Chloro-2-methyl-4-(trifluoromethoxy)benzene-1-sulfonyl chloride; 2-Methyl-5-chloro-4-(trifluoromethoxy)benzenesulfonyl chloride; 4-Trifluoromethoxy-5-chloro-o-toluenesulfonyl chloride; 1706447-06-4; 5-Chloro-2-methyl-4-trifluoromethoxybenzenesulfonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 5-Chloro-2-Methyl-4-(Trifluoromethoxy)Benzenesulfonyl Chloride is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with exacting industry standards and customer specifications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.